相互作用
Armodafinil + Ethinylestradiol
重症度: 重大
Armodafinil and Ethinylestradiol: major interaction.
最終更新日
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概要
Armodafinil can lower ethinylestradiol exposure and may reduce the effectiveness of hormonal contraceptives, with a risk of unintended pregnancy. This effect may persist for about a month after armodafinil is stopped.
この相互作用をわかりやすく説明すると
Armodafinil and Ethinylestradiol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Armodafinil induces CYP3A4, increasing the metabolism of ethinylestradiol.
対処法
Advise an additional or alternative non-hormonal contraceptive method during armodafinil therapy and for one month after stopping it.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ArmodafinilとEthinylestradiolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Armodafinilのその他の相互作用
よくある質問
Can I take Armodafinil with Ethinylestradiol?
MediHelp rates the interaction as major. Armodafinil and Ethinylestradiol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Armodafinil can lower ethinylestradiol exposure and may reduce the effectiveness of hormonal contraceptives, with a risk of unintended pregnancy. This effect may persist for about a month after armodafinil is stopped.
How serious is the interaction between Armodafinil and Ethinylestradiol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise an additional or alternative non-hormonal contraceptive method during armodafinil therapy and for one month after stopping it.
What other medicines interact with Armodafinil?
MediHelp also lists interactions of Armodafinil with, for example, Avapritinib, Cyclosporine, Elacestrant. The full list is on the Armodafinil page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
