相互作用
Asenapine + Carbinoxamine
重症度: 中等度
Asenapine and Carbinoxamine: moderate interaction.
最終更新日
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概要
Carbinoxamine is a sedating first-generation antihistamine with anticholinergic effects, and asenapine is also sedating. Together they increase drowsiness, impair performance and may add anticholinergic effects.
この相互作用をわかりやすく説明すると
Asenapine and Carbinoxamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Asenapine belongs to Central Nervous System; Carbinoxamine belongs to Respiratory.
なぜ起こるのか
Additive CNS depression via histamine H1 blockade and antipsychotic receptor antagonism.
対処法
Advise against driving or hazardous tasks and monitor for oversedation. Consider a non-sedating antihistamine.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AsenapineとCarbinoxamineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Asenapineのその他の相互作用
Carbinoxamineのその他の相互作用
よくある質問
Can I take Asenapine with Carbinoxamine?
MediHelp rates the interaction as moderate. Asenapine and Carbinoxamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbinoxamine is a sedating first-generation antihistamine with anticholinergic effects, and asenapine is also sedating. Together they increase drowsiness, impair performance and may add anticholinergic effects.
How serious is the interaction between Asenapine and Carbinoxamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise against driving or hazardous tasks and monitor for oversedation. Consider a non-sedating antihistamine.
What other medicines interact with Asenapine?
MediHelp also lists interactions of Asenapine with, for example, Pimozide, Thioridazine, Vandetanib. The full list is on the Asenapine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
