相互作用
Amitriptyline + Carbinoxamine
重症度: 中等度
Amitriptyline and Carbinoxamine: moderate interaction.
最終更新日
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概要
Carbinoxamine is a sedating antihistamine with anticholinergic properties, and amitriptyline has the same type of effects. Together they can increase drowsiness, dry mouth, urinary retention, and confusion.
この相互作用をわかりやすく説明すると
Amitriptyline and Carbinoxamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amitriptyline belongs to Central Nervous System; Carbinoxamine belongs to Respiratory.
なぜ起こるのか
Additive CNS depression and antimuscarinic effects.
対処法
Monitor for sedation and anticholinergic effects, and avoid in older patients where possible. Consider a non-sedating antihistamine as an alternative.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmitriptylineとCarbinoxamineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amitriptylineのその他の相互作用
Carbinoxamineのその他の相互作用
よくある質問
Can I take Amitriptyline with Carbinoxamine?
MediHelp rates the interaction as moderate. Amitriptyline and Carbinoxamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbinoxamine is a sedating antihistamine with anticholinergic properties, and amitriptyline has the same type of effects. Together they can increase drowsiness, dry mouth, urinary retention, and confusion.
How serious is the interaction between Amitriptyline and Carbinoxamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for sedation and anticholinergic effects, and avoid in older patients where possible. Consider a non-sedating antihistamine as an alternative.
What other medicines interact with Amitriptyline?
MediHelp also lists interactions of Amitriptyline with, for example, Isocarboxazid, Methylene blue, Phenelzine. The full list is on the Amitriptyline page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
