相互作用
Aspirin / citric acid / sodium bicarbonate + Ketorolac
重症度: 併用禁忌
Aspirin / citric acid / sodium bicarbonate and Ketorolac: contraindicated interaction.
最終更新日
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概要
Ketorolac labeling contraindicates use with aspirin and other NSAIDs. The effervescent aspirin product delivers analgesic-dose aspirin, so bleeding, ulcer and renal risks are additive.
この相互作用をわかりやすく説明すると
Aspirin / citric acid / sodium bicarbonate and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Additive cyclooxygenase inhibition causing GI mucosal injury, platelet inhibition and reduced renal prostaglandins.
対処法
Do not use together. Choose a non-NSAID analgesic such as paracetamol instead of one of the agents.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Aspirin / citric acid / sodium bicarbonateとKetorolacの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ketorolacのその他の相互作用
よくある質問
Can I take Aspirin / citric acid / sodium bicarbonate with Ketorolac?
MediHelp rates the interaction as contraindicated. Aspirin / citric acid / sodium bicarbonate and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac labeling contraindicates use with aspirin and other NSAIDs. The effervescent aspirin product delivers analgesic-dose aspirin, so bleeding, ulcer and renal risks are additive.
How serious is the interaction between Aspirin / citric acid / sodium bicarbonate and Ketorolac?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together. Choose a non-NSAID analgesic such as paracetamol instead of one of the agents.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
