相互作用
Atorvastatin + Niacin
重症度: 中等度
Atorvastatin and Niacin: moderate interaction.
最終更新日
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概要
Lipid-modifying doses of niacin may add to the myopathy risk of atorvastatin. Cases of muscle toxicity have been reported, though the overall risk is low.
この相互作用をわかりやすく説明すると
Atorvastatin and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atorvastatin belongs to Cardiovascular; Niacin belongs to Cardiovascular.
なぜ起こるのか
Additive myotoxicity; niacin may also have a minor pharmacokinetic effect.
対処法
Counsel patients to report muscle pain or weakness and check CK when symptomatic. Use the lowest effective doses.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AtorvastatinとNiacinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Atorvastatinのその他の相互作用
Niacinのその他の相互作用
よくある質問
Can I take Atorvastatin with Niacin?
MediHelp rates the interaction as moderate. Atorvastatin and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lipid-modifying doses of niacin may add to the myopathy risk of atorvastatin. Cases of muscle toxicity have been reported, though the overall risk is low.
How serious is the interaction between Atorvastatin and Niacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to report muscle pain or weakness and check CK when symptomatic. Use the lowest effective doses.
What other medicines interact with Atorvastatin?
MediHelp also lists interactions of Atorvastatin with, for example, Tipranavir, Atazanavir, Clarithromycin. The full list is on the Atorvastatin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
