相互作用
Avanafil + Clarithromycin
重症度: 併用禁忌
Avanafil and Clarithromycin: contraindicated interaction.
最終更新日
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概要
Clarithromycin is a strong CYP3A4 inhibitor and markedly increases avanafil exposure. Hypotension, priapism and cardiovascular events are more likely.
この相互作用をわかりやすく説明すると
Avanafil and Clarithromycin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Avanafil belongs to Genitourinary; Clarithromycin belongs to Anti Bacterial.
なぜ起こるのか
Strong CYP3A4 inhibition increases avanafil exposure
対処法
Do not use together; choose a different PDE5 inhibitor or antimicrobial.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AvanafilとClarithromycinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Avanafilのその他の相互作用
Clarithromycinのその他の相互作用
よくある質問
Can I take Avanafil with Clarithromycin?
MediHelp rates the interaction as contraindicated. Avanafil and Clarithromycin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Clarithromycin is a strong CYP3A4 inhibitor and markedly increases avanafil exposure. Hypotension, priapism and cardiovascular events are more likely.
How serious is the interaction between Avanafil and Clarithromycin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; choose a different PDE5 inhibitor or antimicrobial.
What other medicines interact with Avanafil?
MediHelp also lists interactions of Avanafil with, for example, Amyl nitrite, Atazanavir, Conivaptan. The full list is on the Avanafil page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
