相互作用
Bcg vaccine live + Cefazolin
重症度: 中等度
Bcg vaccine live and Cefazolin: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Live BCG is a viable bacterium, and an active antibiotic may reduce its viability in the host. Cefazolin has little expected activity against BCG, and single perioperative doses are unlikely to matter.
この相互作用をわかりやすく説明すると
Bcg vaccine live and Cefazolin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Antibacterial activity could reduce replication of the live attenuated organism, though cephalosporin activity against BCG is limited.
対処法
Where timing is flexible, give BCG after the antibiotic course is complete. Do not delay urgent vaccination solely because of cefazolin.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Bcg vaccine liveとCefazolinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Cefazolinのその他の相互作用
よくある質問
Can I take Bcg vaccine live with Cefazolin?
MediHelp rates the interaction as moderate. Bcg vaccine live and Cefazolin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Live BCG is a viable bacterium, and an active antibiotic may reduce its viability in the host. Cefazolin has little expected activity against BCG, and single perioperative doses are unlikely to matter.
How serious is the interaction between Bcg vaccine live and Cefazolin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where timing is flexible, give BCG after the antibiotic course is complete. Do not delay urgent vaccination solely because of cefazolin.
What other medicines interact with Cefazolin?
MediHelp also lists interactions of Cefazolin with, for example, Amikacin, Cholera vaccine, Dexamethasone-tobramycin. The full list is on the Cefazolin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。