相互作用
Cefazolin + Dexamethasone-tobramycin
重症度: 中等度
Cefazolin and Dexamethasone-tobramycin: moderate interaction.
最終更新日
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概要
Cefazolin with an aminoglycoside has been linked to additive kidney injury in some reports, though cefazolin itself is rarely nephrotoxic. Risk is greater with pre-existing renal impairment.
この相互作用をわかりやすく説明すると
Cefazolin and Dexamethasone-tobramycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefazolin belongs to Anti Bacterial; Dexamethasone-tobramycin belongs to Anti Bacterial.
なぜ起こるのか
Possible additive nephrotoxicity; mechanism not firmly established.
対処法
Monitor serum creatinine and tobramycin concentrations, and adjust doses for renal function.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CefazolinとDexamethasone-tobramycinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dexamethasone-tobramycinのその他の相互作用
Cefazolinのその他の相互作用
よくある質問
Can I take Cefazolin with Dexamethasone-tobramycin?
MediHelp rates the interaction as moderate. Cefazolin and Dexamethasone-tobramycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefazolin with an aminoglycoside has been linked to additive kidney injury in some reports, though cefazolin itself is rarely nephrotoxic. Risk is greater with pre-existing renal impairment.
How serious is the interaction between Cefazolin and Dexamethasone-tobramycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and tobramycin concentrations, and adjust doses for renal function.
What other medicines interact with Dexamethasone-tobramycin?
MediHelp also lists interactions of Dexamethasone-tobramycin with, for example, Capreomycin, Carboplatin, Ciprofloxacin. The full list is on the Dexamethasone-tobramycin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
