相互作用
Bcg vaccine live + Etanercept
重症度: 併用禁忌
Bcg vaccine live and Etanercept: contraindicated interaction.
最終更新日
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概要
BCG is a live attenuated vaccine, and in a patient receiving TNF blockade the vaccine organism may replicate without adequate control. This can lead to local or disseminated BCG infection. The vaccine response may also be blunted.
この相互作用をわかりやすく説明すると
Bcg vaccine live and Etanercept are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
TNF inhibition impairs granuloma formation and mycobacterial containment, so the live attenuated organism can proliferate.
対処法
Do not give BCG to patients on etanercept. Complete the vaccination before starting etanercept, ideally at least 4 weeks beforehand, or defer it until the drug has been stopped for an adequate washout period.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Bcg vaccine liveとEtanerceptの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Etanerceptのその他の相互作用
よくある質問
Can I take Bcg vaccine live with Etanercept?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Etanercept are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG is a live attenuated vaccine, and in a patient receiving TNF blockade the vaccine organism may replicate without adequate control. This can lead to local or disseminated BCG infection. The vaccine response may also be blunted.
How serious is the interaction between Bcg vaccine live and Etanercept?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG to patients on etanercept. Complete the vaccination before starting etanercept, ideally at least 4 weeks beforehand, or defer it until the drug has been stopped for an adequate washout period.
What other medicines interact with Etanercept?
MediHelp also lists interactions of Etanercept with, for example, Golimumab, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Etanercept page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
