相互作用
Etanercept + Golimumab
重症度: 併用禁忌
Etanercept and Golimumab: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Both agents are TNF-alpha inhibitors, so combining them duplicates therapy without added benefit. Studies of TNF blocker combinations showed more serious infections and adverse events.
この相互作用をわかりやすく説明すると
Etanercept and Golimumab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Etanercept belongs to Musculoskeletal; Golimumab belongs to Musculoskeletal.
なぜ起こるのか
Duplicate TNF-alpha blockade causing additive immunosuppression.
対処法
Do not combine two TNF inhibitors. Use a single agent and switch to another class if response is inadequate.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、EtanerceptとGolimumabの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Golimumabのその他の相互作用
Etanerceptのその他の相互作用
よくある質問
Can I take Etanercept with Golimumab?
MediHelp rates the interaction as contraindicated. Etanercept and Golimumab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents are TNF-alpha inhibitors, so combining them duplicates therapy without added benefit. Studies of TNF blocker combinations showed more serious infections and adverse events.
How serious is the interaction between Etanercept and Golimumab?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine two TNF inhibitors. Use a single agent and switch to another class if response is inadequate.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Golimumab page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
