相互作用
Caffeine + Regadenoson
重症度: 中等度
Caffeine and Regadenoson: moderate interaction.
最終更新日
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概要
Caffeine and other methylxanthines block adenosine receptors, which is how regadenoson produces coronary vasodilation. Recent caffeine intake can blunt the vasodilator response and lead to a false-negative or less reliable myocardial perfusion stress test.
この相互作用をわかりやすく説明すると
Caffeine and Regadenoson can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Caffeine belongs to Miscellaneous; Regadenoson belongs to Cardiovascular.
なぜ起こるのか
Competitive antagonism of adenosine A2A receptors by caffeine opposing the agonist action of regadenoson.
対処法
Withhold caffeine and other methylxanthines (coffee, tea, cola, theophylline) for at least 12 hours before the stress test, or per local protocol. Reschedule the test if recent intake is confirmed.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、CaffeineとRegadenosonの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Caffeineのその他の相互作用
Regadenosonのその他の相互作用
よくある質問
Can I take Caffeine with Regadenoson?
MediHelp rates the interaction as moderate. Caffeine and Regadenoson can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Caffeine and other methylxanthines block adenosine receptors, which is how regadenoson produces coronary vasodilation. Recent caffeine intake can blunt the vasodilator response and lead to a false-negative or less reliable myocardial perfusion stress test.
How serious is the interaction between Caffeine and Regadenoson?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Withhold caffeine and other methylxanthines (coffee, tea, cola, theophylline) for at least 12 hours before the stress test, or per local protocol. Reschedule the test if recent intake is confirmed.
What other medicines interact with Caffeine?
MediHelp also lists interactions of Caffeine with, for example, Ephedrine, Fezolinetant, Methylenedioxymethamphetamine. The full list is on the Caffeine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。