相互作用
Calcium acetate + Captopril-hydrochlorothiazide
重症度: 中等度
Calcium acetate and Captopril-hydrochlorothiazide: moderate interaction.
最終更新日
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概要
Thiazides reduce urinary calcium excretion, so supplemental calcium can raise serum calcium. High calcium intake with thiazides can lead to hypercalcemia and, with absorbable alkali, milk-alkali syndrome.
この相互作用をわかりやすく説明すると
Calcium acetate and Captopril-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium acetate belongs to Genitourinary; Captopril-hydrochlorothiazide belongs to Cardiovascular.
なぜ起こるのか
Thiazides enhance distal tubular calcium reabsorption, reducing renal calcium clearance.
対処法
Monitor serum calcium periodically and reduce the calcium dose if hypercalcemia develops, especially in renal impairment.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、Calcium acetateとCaptopril-hydrochlorothiazideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Captopril-hydrochlorothiazideのその他の相互作用
Calcium acetateのその他の相互作用
よくある質問
Can I take Calcium acetate with Captopril-hydrochlorothiazide?
MediHelp rates the interaction as moderate. Calcium acetate and Captopril-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thiazides reduce urinary calcium excretion, so supplemental calcium can raise serum calcium. High calcium intake with thiazides can lead to hypercalcemia and, with absorbable alkali, milk-alkali syndrome.
How serious is the interaction between Calcium acetate and Captopril-hydrochlorothiazide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium periodically and reduce the calcium dose if hypercalcemia develops, especially in renal impairment.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
