相互作用
Cangrelor + Warfarin
重症度: 中等度
Cangrelor and Warfarin: moderate interaction.
最終更新日
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概要
Cangrelor is an intravenous P2Y12 inhibitor with a very short action. With warfarin, bleeding risk increases while it is infused, because platelet and coagulation pathways are both inhibited.
この相互作用をわかりやすく説明すると
Cangrelor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cangrelor belongs to Cardiovascular; Warfarin belongs to Cardiovascular.
なぜ起こるのか
Additive pharmacodynamic effect of P2Y12 platelet inhibition and vitamin K antagonist anticoagulation.
対処法
Monitor for bleeding and hemoglobin during and after the infusion, and check INR as needed. Reassess the need for combined antithrombotic therapy.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CangrelorとWarfarinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Warfarinのその他の相互作用
Cangrelorのその他の相互作用
よくある質問
Can I take Cangrelor with Warfarin?
MediHelp rates the interaction as moderate. Cangrelor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cangrelor is an intravenous P2Y12 inhibitor with a very short action. With warfarin, bleeding risk increases while it is infused, because platelet and coagulation pathways are both inhibited.
How serious is the interaction between Cangrelor and Warfarin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and hemoglobin during and after the infusion, and check INR as needed. Reassess the need for combined antithrombotic therapy.
What other medicines interact with Warfarin?
MediHelp also lists interactions of Warfarin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Warfarin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
