相互作用
Carvedilol + Umeclidinium-vilanterol
重症度: 重大
Carvedilol and Umeclidinium-vilanterol: major interaction.
最終更新日
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概要
Carvedilol is a non-selective beta-blocker and can block the bronchodilating effect of vilanterol. It may provoke bronchospasm in patients with asthma or COPD.
この相互作用をわかりやすく説明すると
Carvedilol and Umeclidinium-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Carvedilol belongs to Cardiovascular; Umeclidinium-vilanterol belongs to Respiratory.
なぜ起こるのか
Pharmacodynamic antagonism through beta-2 receptor blockade.
対処法
Prefer a beta-1 selective blocker such as bisoprolol or metoprolol where a beta-blocker is needed. Monitor lung function and symptoms if carvedilol is continued.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CarvedilolとUmeclidinium-vilanterolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Umeclidinium-vilanterolのその他の相互作用
Carvedilolのその他の相互作用
よくある質問
Can I take Carvedilol with Umeclidinium-vilanterol?
MediHelp rates the interaction as major. Carvedilol and Umeclidinium-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Carvedilol is a non-selective beta-blocker and can block the bronchodilating effect of vilanterol. It may provoke bronchospasm in patients with asthma or COPD.
How serious is the interaction between Carvedilol and Umeclidinium-vilanterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prefer a beta-1 selective blocker such as bisoprolol or metoprolol where a beta-blocker is needed. Monitor lung function and symptoms if carvedilol is continued.
What other medicines interact with Umeclidinium-vilanterol?
MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amitriptyline. The full list is on the Umeclidinium-vilanterol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
