相互作用
Cefalexin + Cholera vaccine
重症度: 中等度
Cefalexin and Cholera vaccine: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Oral live attenuated cholera vaccine requires viable bacteria to colonize the gut. Systemic antibiotics may kill the vaccine strain and reduce the immune response. Cefalexin activity against Vibrio is limited, so the effect is possibly smaller than with broader agents.
この相互作用をわかりやすく説明すると
Cefalexin and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Possible antibacterial activity against the live attenuated vaccine strain lowers its viability and immunogenicity.
対処法
Follow labeling by avoiding vaccination within 14 days after systemic antibiotics. Delay antibiotic use after vaccination if clinically acceptable.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CefalexinとCholera vaccineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cefalexinのその他の相互作用
よくある質問
Can I take Cefalexin with Cholera vaccine?
MediHelp rates the interaction as moderate. Cefalexin and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral live attenuated cholera vaccine requires viable bacteria to colonize the gut. Systemic antibiotics may kill the vaccine strain and reduce the immune response. Cefalexin activity against Vibrio is limited, so the effect is possibly smaller than with broader agents.
How serious is the interaction between Cefalexin and Cholera vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Follow labeling by avoiding vaccination within 14 days after systemic antibiotics. Delay antibiotic use after vaccination if clinically acceptable.
What other medicines interact with Cefalexin?
MediHelp also lists interactions of Cefalexin with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefalexin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
