相互作用
Cholestyramine + Liothyronine
重症度: 中等度
Cholestyramine and Liothyronine: moderate interaction.
最終更新日
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概要
Cholestyramine binds thyroid hormones in the gut and markedly reduces absorption of oral liothyronine. This can cause hypothyroid symptoms and raised TSH.
この相互作用をわかりやすく説明すると
Cholestyramine and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cholestyramine belongs to Cardiovascular; Liothyronine belongs to Endocrine.
なぜ起こるのか
Resin binding of liothyronine in the gastrointestinal tract reduces absorption and may interrupt enterohepatic recirculation.
対処法
Separate liothyronine from cholestyramine by at least 4 hours. Monitor TSH and adjust the thyroid dose if needed.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CholestyramineとLiothyronineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cholestyramineのその他の相互作用
Liothyronineのその他の相互作用
よくある質問
Can I take Cholestyramine with Liothyronine?
MediHelp rates the interaction as moderate. Cholestyramine and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cholestyramine binds thyroid hormones in the gut and markedly reduces absorption of oral liothyronine. This can cause hypothyroid symptoms and raised TSH.
How serious is the interaction between Cholestyramine and Liothyronine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate liothyronine from cholestyramine by at least 4 hours. Monitor TSH and adjust the thyroid dose if needed.
What other medicines interact with Cholestyramine?
MediHelp also lists interactions of Cholestyramine with, for example, Cholic acid, Deferasirox, Leflunomide. The full list is on the Cholestyramine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
