相互作用
Carbamazepine + Liothyronine
重症度: 中等度
Carbamazepine and Liothyronine: moderate interaction.
最終更新日
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概要
Carbamazepine can lower thyroid hormone levels, and patients on liothyronine may become under-replaced. Hypothyroid symptoms may appear.
この相互作用をわかりやすく説明すると
Carbamazepine and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbamazepine belongs to Central Nervous System; Liothyronine belongs to Endocrine.
なぜ起こるのか
Carbamazepine induces hepatic metabolism and glucuronidation of thyroid hormones.
対処法
Monitor TSH and free thyroid hormones after starting or stopping carbamazepine. Increase the liothyronine dose if clinically hypothyroid.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CarbamazepineとLiothyronineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Carbamazepineのその他の相互作用
Liothyronineのその他の相互作用
よくある質問
Can I take Carbamazepine with Liothyronine?
MediHelp rates the interaction as moderate. Carbamazepine and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbamazepine can lower thyroid hormone levels, and patients on liothyronine may become under-replaced. Hypothyroid symptoms may appear.
How serious is the interaction between Carbamazepine and Liothyronine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor TSH and free thyroid hormones after starting or stopping carbamazepine. Increase the liothyronine dose if clinically hypothyroid.
What other medicines interact with Carbamazepine?
MediHelp also lists interactions of Carbamazepine with, for example, Artemether / lumefantrine, Cabotegravir, Delamanid. The full list is on the Carbamazepine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
