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相互作用

Cortisone + Human papillomavirus vaccine

重症度: 中等度

Cortisone and Human papillomavirus vaccine: moderate interaction.

最終更新日

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概要

Systemic corticosteroids at higher than physiologic doses suppress immune function and may reduce the antibody response to vaccines. Protection after HPV vaccination may be lower in patients on sustained high-dose therapy.

この相互作用をわかりやすく説明すると

Cortisone and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

エビデンスレベル: Moderate

なぜ起こるのか

Glucocorticoid-mediated suppression of lymphocyte function reduces vaccine immunogenicity.

対処法

Non-live HPV vaccine can be given to patients on corticosteroids. Where possible vaccinate when the dose is low or before starting prolonged high-dose therapy, and consider checking response.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、CortisoneとHuman papillomavirus vaccineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Cortisone with Human papillomavirus vaccine?

MediHelp rates the interaction as moderate. Cortisone and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroids at higher than physiologic doses suppress immune function and may reduce the antibody response to vaccines. Protection after HPV vaccination may be lower in patients on sustained high-dose therapy.

How serious is the interaction between Cortisone and Human papillomavirus vaccine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Non-live HPV vaccine can be given to patients on corticosteroids. Where possible vaccinate when the dose is low or before starting prolonged high-dose therapy, and consider checking response.

What other medicines interact with Human papillomavirus vaccine?

MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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