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相互作用

Demeclocycline + Dicloxacillin

重症度: 中等度

Demeclocycline and Dicloxacillin: moderate interaction.

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概要

Bacteriostatic tetracyclines can reduce the killing effect of penicillins on bacteria that need active growth. Evidence is mostly in vitro and from older reports, but it may matter in serious infections.

この相互作用をわかりやすく説明すると

Demeclocycline and Dicloxacillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

エビデンスレベル: Low

なぜ起こるのか

Tetracycline-induced inhibition of bacterial growth reduces the activity of cell-wall-active beta-lactams.

対処法

Avoid combining in serious infections that need bactericidal therapy. If unavoidable, monitor clinical response closely.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、DemeclocyclineとDicloxacillinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Demeclocycline with Dicloxacillin?

MediHelp rates the interaction as moderate. Demeclocycline and Dicloxacillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bacteriostatic tetracyclines can reduce the killing effect of penicillins on bacteria that need active growth. Evidence is mostly in vitro and from older reports, but it may matter in serious infections.

How serious is the interaction between Demeclocycline and Dicloxacillin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining in serious infections that need bactericidal therapy. If unavoidable, monitor clinical response closely.

What other medicines interact with Dicloxacillin?

MediHelp also lists interactions of Dicloxacillin with, for example, Phenindione, Atogepant, Axitinib. The full list is on the Dicloxacillin page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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