相互作用
Demeclocycline + Penicillin g
重症度: 中等度
Demeclocycline and Penicillin g: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Bacteriostatic tetracyclines can in theory blunt the activity of bactericidal beta-lactams that depend on cell growth. Clinical evidence is limited and mostly from older studies in serious infections such as meningitis.
この相互作用をわかりやすく説明すると
Demeclocycline and Penicillin g can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Bacteriostatic inhibition of protein synthesis by demeclocycline may reduce the bactericidal action of penicillin on actively dividing bacteria.
対処法
Avoid combining them for serious infections such as meningitis or endocarditis, and choose a single bactericidal regimen where possible.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DemeclocyclineとPenicillin gの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Penicillin gのその他の相互作用
よくある質問
Can I take Demeclocycline with Penicillin g?
MediHelp rates the interaction as moderate. Demeclocycline and Penicillin g can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bacteriostatic tetracyclines can in theory blunt the activity of bactericidal beta-lactams that depend on cell growth. Clinical evidence is limited and mostly from older studies in serious infections such as meningitis.
How serious is the interaction between Demeclocycline and Penicillin g?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining them for serious infections such as meningitis or endocarditis, and choose a single bactericidal regimen where possible.
What other medicines interact with Penicillin g?
MediHelp also lists interactions of Penicillin g with, for example, Amifampridine, Amiloride, Bcg vaccine live. The full list is on the Penicillin g page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
