相互作用
Dextroamphetamine transdermal + Vitamin c
重症度: 中等度
Dextroamphetamine transdermal and Vitamin c: moderate interaction.
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概要
Ascorbic acid in large doses can acidify the urine, which increases renal excretion of amphetamines and may reduce their effect. The effect is most relevant with high-dose vitamin C.
この相互作用をわかりやすく説明すると
Dextroamphetamine transdermal and Vitamin c can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Urinary acidification ionizes amphetamine and reduces renal tubular reabsorption, increasing clearance.
対処法
Avoid high-dose vitamin C or acidifying agents during amphetamine therapy. Reassess clinical response and adjust the dose if needed.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、Dextroamphetamine transdermalとVitamin cの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Vitamin cのその他の相互作用
よくある質問
Can I take Dextroamphetamine transdermal with Vitamin c?
MediHelp rates the interaction as moderate. Dextroamphetamine transdermal and Vitamin c can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ascorbic acid in large doses can acidify the urine, which increases renal excretion of amphetamines and may reduce their effect. The effect is most relevant with high-dose vitamin C.
How serious is the interaction between Dextroamphetamine transdermal and Vitamin c?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid high-dose vitamin C or acidifying agents during amphetamine therapy. Reassess clinical response and adjust the dose if needed.
What other medicines interact with Vitamin c?
MediHelp also lists interactions of Vitamin c with, for example, Deferoxamine, Aluminum hydroxide, Aspirin / citric acid / sodium bicarbonate. The full list is on the Vitamin c page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。