相互作用
Ertapenem + Typhoid vaccine live
重症度: 重大
Ertapenem and Typhoid vaccine live: major interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Oral live typhoid vaccine depends on viable attenuated Salmonella Typhi in the gut. Ertapenem is active against Salmonella and may reduce vaccine viability and the immune response.
この相互作用をわかりやすく説明すると
Ertapenem and Typhoid vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Antibacterial activity inhibits the live attenuated Salmonella strain, reducing immunogenicity.
対処法
Give live oral typhoid vaccine at least 3 days after the last ertapenem dose, or vaccinate beforehand. Use the inactivated parenteral vaccine if timing cannot be separated.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ErtapenemとTyphoid vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ertapenemのその他の相互作用
よくある質問
Can I take Ertapenem with Typhoid vaccine live?
MediHelp rates the interaction as major. Ertapenem and Typhoid vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral live typhoid vaccine depends on viable attenuated Salmonella Typhi in the gut. Ertapenem is active against Salmonella and may reduce vaccine viability and the immune response.
How serious is the interaction between Ertapenem and Typhoid vaccine live?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give live oral typhoid vaccine at least 3 days after the last ertapenem dose, or vaccinate beforehand. Use the inactivated parenteral vaccine if timing cannot be separated.
What other medicines interact with Ertapenem?
MediHelp also lists interactions of Ertapenem with, for example, Valproic acid, Cholera vaccine, Microbiota. The full list is on the Ertapenem page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
