医薬品リファレンス
Ertapenem
Ertapenem is a medicine in the class anti bacterial. It is used for female pelvic infections.
- 薬効分類: Anti Bacterial
- 効能・効果: female pelvic infections
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Anti Bacterial
- ATCコード
- J01DH03
- 一般的な剤形
- 注射剤, 点滴静注剤
- 一般的な規格
- 1 g, 1000 mg
- 既知の相互作用
- 7 (併用禁忌: 1 · 重大: 1 · 中等度: 3 · 軽度: 2)
- 商品名
- 8
- 国・市場
- 5
何に使われるか
作用のしくみ
1-beta methyl-carbapenem; inhibits cell-wall synthesis by binding to penicillin-binding proteins; resistant to most beta-lactamases.
成人の通常用量（添付文書の要約）
Community-Acquired Pneumonia: 1 g/day IV/IM up to 14 days; after ≥3 days of parenteral therapy, may be switched to appropriate PO regimen if patient improves clinically
妊娠と授乳
- 妊娠
- Safe Limited human data; no birth defects in rats or mice. EU label: use only if benefit outweighs risk. Beta-lactams are generally acceptable in pregnancy; use when needed for serious infection.
- 授乳
- Safe EU label: do not breastfeed during treatment. LactMed: milk levels are low, undetectable by 5 days after stopping, and not expected to harm the infant; acceptable. Watch for diarrhoea or thrush.
報告されている副作用
- Headache
- Diarrhea
- Nausea
- Elevated liver function tests (LFTs)
- Infused vein complications
禁忌
- Hypersensitivity to ertapenem, beta-lactams, or other drugs in this class
- IM administration: Hypersensitivity to amide local anesthetics (eg, lidocaine)
注意が必要な方
- Use caution in renal impairment; adjust dose in moderate to severe renal dysfunction
- Use with caution in CNS disorders (eg., history of seizures); adjust dose in renal impairment to avoid risk of seizures; carbapenem use has been associated with seizures
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (7)
- Ertapenem + Valproic acid Contraindicated
- Ertapenem + Typhoid vaccine live Major
- Cholera vaccine + Ertapenem Moderate
- Ertapenem + Microbiota Moderate
- Ertapenem + Sodium picosulfate / magnesium oxide / anhydrous citric acid Moderate
- Bcg vaccine live + Ertapenem Minor
- Ertapenem + Probenecid Minor
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Ertapenemの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
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同じ分類のほかの薬剤
よくある質問
What is Ertapenem used for?
Ertapenem is a medicine in the class anti bacterial. It is used for Female pelvic infections, Intra-abdominal infections, Pneumonia, Skin infections, Urinary tract infections.
What side effects have been reported with Ertapenem?
Headache, Diarrhea, Nausea, Elevated liver function tests (LFTs), Infused vein complications.
Can Ertapenem be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Limited human data; no birth defects in rats or mice. EU label: use only if benefit outweighs risk. Beta-lactams are generally acceptable in pregnancy; use when needed for serious infection. Breastfeeding: Safe. EU label: do not breastfeed during treatment. LactMed: milk levels are low, undetectable by 5 days after stopping, and not expected to harm the infant; acceptable. Watch for diarrhoea or thrush.
What does Ertapenem interact with?
MediHelp lists 7 known interactions for Ertapenem. Contraindicated: 1 · Major: 1 · Moderate: 3 · Minor: 2. The most serious include Valproic acid, Typhoid vaccine live, Cholera vaccine.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
