相互作用
Etodolac + Ketorolac intranasal
重症度: 併用禁忌
Etodolac and Ketorolac intranasal: contraindicated interaction.
最終更新日
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概要
Using etodolac with intranasal ketorolac gives duplicate NSAID therapy, increasing the risk of gastrointestinal bleeding or ulceration, renal impairment and cardiovascular events. Intranasal ketorolac is systemically absorbed and carries the same prohibition on concurrent NSAIDs as the oral form.
この相互作用をわかりやすく説明すると
Etodolac and Ketorolac intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Additive cyclooxygenase inhibition producing additive gastrointestinal, renal, platelet and cardiovascular toxicity.
対処法
Avoid the combination; use a single NSAID. Stop etodolac before starting ketorolac, or choose a non-NSAID analgesic.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、EtodolacとKetorolac intranasalの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Etodolacのその他の相互作用
よくある質問
Can I take Etodolac with Ketorolac intranasal?
MediHelp rates the interaction as contraindicated. Etodolac and Ketorolac intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Using etodolac with intranasal ketorolac gives duplicate NSAID therapy, increasing the risk of gastrointestinal bleeding or ulceration, renal impairment and cardiovascular events. Intranasal ketorolac is systemically absorbed and carries the same prohibition on concurrent NSAIDs as the oral form.
How serious is the interaction between Etodolac and Ketorolac intranasal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; use a single NSAID. Stop etodolac before starting ketorolac, or choose a non-NSAID analgesic.
What other medicines interact with Etodolac?
MediHelp also lists interactions of Etodolac with, for example, Ketorolac, Aceclofenac, Acemetacin. The full list is on the Etodolac page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
