相互作用
Etrasimod + Interferon beta 1b
重症度: 重大
Etrasimod and Interferon beta 1b: major interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Etrasimod lowers circulating lymphocyte counts and interferon beta can also affect immune function and cause leukopenia. Combining them could add to immune suppression and raise the risk of infection, and this combination has not been studied. The effect of etrasimod on lymphocytes persists for some weeks after the last dose.
この相互作用をわかりやすく説明すると
Etrasimod and Interferon beta 1b can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Etrasimod belongs to Gastrointestinal Tract; Interferon beta 1b belongs to Central Nervous System.
なぜ起こるのか
Additive immunomodulatory effects: etrasimod sequesters lymphocytes via S1P receptor modulation while interferon beta alters immune function and may reduce blood counts.
対処法
Avoid combining these agents, including during the weeks after etrasimod is stopped. If used, monitor the complete blood count and watch closely for signs of infection.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、EtrasimodとInterferon beta 1bの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Interferon beta 1bのその他の相互作用
Etrasimodのその他の相互作用
よくある質問
Can I take Etrasimod with Interferon beta 1b?
MediHelp rates the interaction as major. Etrasimod and Interferon beta 1b can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Etrasimod lowers circulating lymphocyte counts and interferon beta can also affect immune function and cause leukopenia. Combining them could add to immune suppression and raise the risk of infection, and this combination has not been studied. The effect of etrasimod on lymphocytes persists for some weeks after the last dose.
How serious is the interaction between Etrasimod and Interferon beta 1b?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining these agents, including during the weeks after etrasimod is stopped. If used, monitor the complete blood count and watch closely for signs of infection.
What other medicines interact with Interferon beta 1b?
MediHelp also lists interactions of Interferon beta 1b with, for example, Axicabtagene ciloleucel, Brexucabtagene autoleucel, Ciltacabtagene autoleucel. The full list is on the Interferon beta 1b page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
