医薬品リファレンス
Interferon beta 1b
Interferon beta 1b is a medicine in the class central nervous system. It is used for multiple sclerosis.
- 薬効分類: Central Nervous System
- 効能・効果: multiple sclerosis
最終更新日
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要点
- 薬効分類
- Central Nervous System
- ATCコード
- L03AB08
- 既知の相互作用
- 20 (重大: 11 · 中等度: 9)
- 商品名
- 1
- 国・市場
- 1
何に使われるか
作用のしくみ
Recombinant interferon; antiviral, antiproliferative, immunoregulatory protein; alters response to surface antigen and may inhance immune cell activities
成人の通常用量(添付文書の要約)
0.0625 mg SC every other day initially
妊娠と授乳
- 妊娠
- Safe Registry data (over 1000 pregnancies) show no rise in major birth defects; it caused miscarriage in monkeys at about 3 times the human dose, but human data do not show a clear increase. EU label: may be considered in pregnancy if clinically needed.
- 授乳
- Safe Interferon beta levels in milk are negligible and it is poorly absorbed by mouth. EU label: Betaferon can be used while breastfeeding; no harm to the infant is expected. LactMed: interferon beta is a preferred MS treatment during breastfeeding.
報告されている副作用
- Headache
- Nausea
- Injection site reaction
- Fever
- Chills
- Flu-like syndrome
注意が必要な方
- To reduce injection site reactions; Bring a drug to room temperature before injection, Ice the injection site, and Rotate injection sites.
- Leukopenia may occur; monitor complete blood count
- Depression and suicide reported with increased frequency in patients receiving interferon beta products, including interferon beta-1b;
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (20)
- Axicabtagene ciloleucel + Interferon beta 1b Major
- Brexucabtagene autoleucel + Interferon beta 1b Major
- Ciltacabtagene autoleucel + Interferon beta 1b Major
- Deferiprone + Interferon beta 1b Major
- Etrasimod + Interferon beta 1b Major
- Idecabtagene vicleucel + Interferon beta 1b Major
- Interferon beta 1b + Lisocabtagene maraleucel Major
- Interferon beta 1b + Pexidartinib Major
- Interferon beta 1b + Pretomanid Major
- Interferon beta 1b + Ropeginterferon alfa 2b Major
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Interferon beta 1bの完全なモノグラフ(用量、妊娠・授乳、副作用、警告、すべての相互作用)を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
- IV preparation and dilution
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同じ分類のほかの薬剤
よくある質問
What is Interferon beta 1b used for?
Interferon beta 1b is a medicine in the class central nervous system. It is used for Multiple sclerosis.
What side effects have been reported with Interferon beta 1b?
Headache, Nausea, Injection site reaction, Fever, Chills, Flu-like syndrome.
Can Interferon beta 1b be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Registry data (over 1000 pregnancies) show no rise in major birth defects; it caused miscarriage in monkeys at about 3 times the human dose, but human data do not show a clear increase. EU label: may be considered in pregnancy if clinically needed. Breastfeeding: Safe. Interferon beta levels in milk are negligible and it is poorly absorbed by mouth. EU label: Betaferon can be used while breastfeeding; no harm to the infant is expected. LactMed: interferon beta is a preferred MS treatment during breastfeeding.
What does Interferon beta 1b interact with?
MediHelp lists 20 known interactions for Interferon beta 1b. Major: 11 · Moderate: 9. The most serious include Axicabtagene ciloleucel, Brexucabtagene autoleucel, Ciltacabtagene autoleucel.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。