相互作用
Ferric oxyhydroxide + Levothyroxine
重症度: 中等度
Ferric oxyhydroxide and Levothyroxine: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Iron compounds bind levothyroxine in the gut and reduce its absorption, which may raise TSH and cause hypothyroid symptoms.
この相互作用をわかりやすく説明すると
Ferric oxyhydroxide and Levothyroxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ferric oxyhydroxide belongs to Gastrointestinal Tract; Levothyroxine belongs to Endocrine.
なぜ起こるのか
Formation of insoluble complexes between iron and levothyroxine in the gastrointestinal tract.
対処法
Give levothyroxine at least 4 hours before ferric oxyhydroxide and monitor TSH.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Ferric oxyhydroxideとLevothyroxineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を7日間無料でお試し。カード登録不要。
Ferric oxyhydroxideのその他の相互作用
Levothyroxineのその他の相互作用
よくある質問
Can I take Ferric oxyhydroxide with Levothyroxine?
MediHelp rates the interaction as moderate. Ferric oxyhydroxide and Levothyroxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron compounds bind levothyroxine in the gut and reduce its absorption, which may raise TSH and cause hypothyroid symptoms.
How serious is the interaction between Ferric oxyhydroxide and Levothyroxine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give levothyroxine at least 4 hours before ferric oxyhydroxide and monitor TSH.
What other medicines interact with Ferric oxyhydroxide?
MediHelp also lists interactions of Ferric oxyhydroxide with, for example, Doxycycline, Acetylsalicylic acid, Cefalexin. The full list is on the Ferric oxyhydroxide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。