相互作用
Levothyroxine + Tiratricol
重症度: 重大
Levothyroxine and Tiratricol: major interaction.
最終更新日
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概要
Both agents are thyroid hormone analogues, so combining them adds thyromimetic activity and can cause thyrotoxic effects such as tachycardia and arrhythmia. Tiratricol also suppresses TSH and alters thyroid function tests.
この相互作用をわかりやすく説明すると
Levothyroxine and Tiratricol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Levothyroxine belongs to Endocrine; Tiratricol belongs to Endocrine.
なぜ起こるのか
Additive thyroid hormone receptor agonism.
対処法
Avoid the combination unless specialist-directed. If used, monitor thyroid function tests and heart rate and adjust doses.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、LevothyroxineとTiratricolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Tiratricolのその他の相互作用
Levothyroxineのその他の相互作用
よくある質問
Can I take Levothyroxine with Tiratricol?
MediHelp rates the interaction as major. Levothyroxine and Tiratricol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both agents are thyroid hormone analogues, so combining them adds thyromimetic activity and can cause thyrotoxic effects such as tachycardia and arrhythmia. Tiratricol also suppresses TSH and alters thyroid function tests.
How serious is the interaction between Levothyroxine and Tiratricol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination unless specialist-directed. If used, monitor thyroid function tests and heart rate and adjust doses.
What other medicines interact with Tiratricol?
MediHelp also lists interactions of Tiratricol with, for example, Calcium, Carbamazepine, Carbimazole. The full list is on the Tiratricol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。