相互作用
Foscarnet + Pimozide
重症度: 併用禁忌
Foscarnet and Pimozide: contraindicated interaction.
最終更新日
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概要
Pimozide is a strongly QT-prolonging antipsychotic with documented torsades de pointes risk, and foscarnet adds QT prolongation and electrolyte disturbances. The combination could precipitate life-threatening arrhythmia.
この相互作用をわかりやすく説明すると
Foscarnet and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Foscarnet belongs to Anti Virals; Pimozide belongs to Central Nervous System.
なぜ起こるのか
Additive QT prolongation, amplified by foscarnet-induced hypocalcemia, hypomagnesemia and hypokalemia.
対処法
Do not combine; use an alternative to pimozide for the duration of foscarnet therapy.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、FoscarnetとPimozideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Foscarnetのその他の相互作用
Pimozideのその他の相互作用
よくある質問
Can I take Foscarnet with Pimozide?
MediHelp rates the interaction as contraindicated. Foscarnet and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Pimozide is a strongly QT-prolonging antipsychotic with documented torsades de pointes risk, and foscarnet adds QT prolongation and electrolyte disturbances. The combination could precipitate life-threatening arrhythmia.
How serious is the interaction between Foscarnet and Pimozide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use an alternative to pimozide for the duration of foscarnet therapy.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Thioridazine, Vandetanib. The full list is on the Foscarnet page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
