相互作用
Foscarnet + Thioridazine
重症度: 併用禁忌
Foscarnet and Thioridazine: contraindicated interaction.
最終更新日
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概要
Thioridazine is strongly associated with QT prolongation and torsades de pointes, and foscarnet adds further QT risk and electrolyte depletion. The combination carries a high risk of life-threatening arrhythmia.
この相互作用をわかりやすく説明すると
Foscarnet and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Foscarnet belongs to Anti Virals; Thioridazine belongs to Central Nervous System.
なぜ起こるのか
Additive QT prolongation, with foscarnet-related hypocalcemia and hypomagnesemia increasing susceptibility.
対処法
Avoid the combination and choose an antipsychotic with lower QT liability.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、FoscarnetとThioridazineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Foscarnetのその他の相互作用
Thioridazineのその他の相互作用
よくある質問
Can I take Foscarnet with Thioridazine?
MediHelp rates the interaction as contraindicated. Foscarnet and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Thioridazine is strongly associated with QT prolongation and torsades de pointes, and foscarnet adds further QT risk and electrolyte depletion. The combination carries a high risk of life-threatening arrhythmia.
How serious is the interaction between Foscarnet and Thioridazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose an antipsychotic with lower QT liability.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Vandetanib. The full list is on the Foscarnet page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
