相互作用
Influenza virus vaccine quadrivalent intranasal + Leflunomide
重症度: 併用禁忌
Influenza virus vaccine quadrivalent intranasal and Leflunomide: contraindicated interaction.
最終更新日
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概要
The intranasal influenza vaccine contains live attenuated virus, which may replicate more readily in a patient immunosuppressed by leflunomide. This could cause vaccine-strain infection and the response may be reduced.
この相互作用をわかりやすく説明すると
Influenza virus vaccine quadrivalent intranasal and Leflunomide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Impaired lymphocyte function reduces control of live attenuated virus replication.
対処法
Avoid the live intranasal vaccine; use an inactivated injectable influenza vaccine instead.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Influenza virus vaccine quadrivalent intranasalとLeflunomideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Leflunomideのその他の相互作用
よくある質問
Can I take Influenza virus vaccine quadrivalent intranasal with Leflunomide?
MediHelp rates the interaction as contraindicated. Influenza virus vaccine quadrivalent intranasal and Leflunomide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which may replicate more readily in a patient immunosuppressed by leflunomide. This could cause vaccine-strain infection and the response may be reduced.
How serious is the interaction between Influenza virus vaccine quadrivalent intranasal and Leflunomide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live intranasal vaccine; use an inactivated injectable influenza vaccine instead.
What other medicines interact with Leflunomide?
MediHelp also lists interactions of Leflunomide with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Leflunomide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
