相互作用
Insulin detemir + Insulin glargine-lixisenatide
重症度: 重大
Insulin detemir and Insulin glargine-lixisenatide: major interaction.
最終更新日
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概要
This combination product already contains basal insulin, so adding insulin detemir duplicates basal insulin therapy. The result is a high risk of hypoglycemia from overlapping basal coverage.
この相互作用をわかりやすく説明すると
Insulin detemir and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin detemir belongs to Endocrine; Insulin glargine-lixisenatide belongs to Endocrine.
なぜ起こるのか
Therapeutic duplication with additive insulin effect.
対処法
Avoid using two basal insulins together; use one regimen and adjust doses to the patient's glycemic needs. If switching, stop the other basal insulin and monitor glucose closely.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Insulin detemirとInsulin glargine-lixisenatideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Insulin glargine-lixisenatideのその他の相互作用
Insulin detemirのその他の相互作用
よくある質問
Can I take Insulin detemir with Insulin glargine-lixisenatide?
MediHelp rates the interaction as major. Insulin detemir and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. This combination product already contains basal insulin, so adding insulin detemir duplicates basal insulin therapy. The result is a high risk of hypoglycemia from overlapping basal coverage.
How serious is the interaction between Insulin detemir and Insulin glargine-lixisenatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two basal insulins together; use one regimen and adjust doses to the patient's glycemic needs. If switching, stop the other basal insulin and monitor glucose closely.
What other medicines interact with Insulin glargine-lixisenatide?
MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
