相互作用
Dulaglutide + Insulin glargine-lixisenatide
重症度: 重大
Dulaglutide and Insulin glargine-lixisenatide: major interaction.
最終更新日
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概要
Dulaglutide is a GLP-1 receptor agonist, so combining it with a product that already contains lixisenatide duplicates therapy. It gives no added benefit and increases gastrointestinal adverse effects and hypoglycemia risk.
この相互作用をわかりやすく説明すると
Dulaglutide and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dulaglutide belongs to Endocrine; Insulin glargine-lixisenatide belongs to Endocrine.
なぜ起こるのか
Therapeutic duplication of GLP-1 receptor agonism with additive glucose lowering.
対処法
Avoid using two GLP-1 receptor agonists together; use only one agent.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DulaglutideとInsulin glargine-lixisenatideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Insulin glargine-lixisenatideのその他の相互作用
Dulaglutideのその他の相互作用
よくある質問
Can I take Dulaglutide with Insulin glargine-lixisenatide?
MediHelp rates the interaction as major. Dulaglutide and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dulaglutide is a GLP-1 receptor agonist, so combining it with a product that already contains lixisenatide duplicates therapy. It gives no added benefit and increases gastrointestinal adverse effects and hypoglycemia risk.
How serious is the interaction between Dulaglutide and Insulin glargine-lixisenatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two GLP-1 receptor agonists together; use only one agent.
What other medicines interact with Insulin glargine-lixisenatide?
MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Ethanol. The full list is on the Insulin glargine-lixisenatide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
