相互作用
Isotretinoin + Sarecycline
重症度: 重大
Isotretinoin and Sarecycline: major interaction.
最終更新日
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概要
Oral retinoids and tetracycline-class antibiotics are both linked to idiopathic intracranial hypertension. Combining isotretinoin with sarecycline may increase the risk of headache, visual changes and papilledema.
この相互作用をわかりやすく説明すると
Isotretinoin and Sarecycline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Isotretinoin belongs to Dermatology; Sarecycline belongs to Anti Bacterial.
なぜ起こるのか
Additive risk of raised intracranial pressure; the mechanism is not well established.
対処法
Avoid concurrent use and use a non-tetracycline option for acne during isotretinoin therapy. Stop both and assess urgently if persistent headache or visual symptoms arise.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、IsotretinoinとSarecyclineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Isotretinoinのその他の相互作用
Sarecyclineのその他の相互作用
よくある質問
Can I take Isotretinoin with Sarecycline?
MediHelp rates the interaction as major. Isotretinoin and Sarecycline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral retinoids and tetracycline-class antibiotics are both linked to idiopathic intracranial hypertension. Combining isotretinoin with sarecycline may increase the risk of headache, visual changes and papilledema.
How serious is the interaction between Isotretinoin and Sarecycline?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and use a non-tetracycline option for acne during isotretinoin therapy. Stop both and assess urgently if persistent headache or visual symptoms arise.
What other medicines interact with Isotretinoin?
MediHelp also lists interactions of Isotretinoin with, for example, Demeclocycline, Minocycline, Oxytetracycline. The full list is on the Isotretinoin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
