医薬品リファレンス
Sarecycline
Sarecycline is a medicine in the class anti bacterial. It is used for acne.
- 薬効分類: Anti Bacterial
- 効能・効果: acne
最終更新日 出典: US FDA label
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要点
- 薬効分類
- Anti Bacterial
- 一般的な剤形
- 錠剤
- 既知の相互作用
- 104 (併用禁忌: 1 · 重大: 2 · 中等度: 15 · 軽度: 86)
- 商品名
- 1
- 国・市場
- 1
何に使われるか
作用のしくみ
Sarecycline is an aminomethylcycline within the tetracycline class. Its mechanism in treating inflammatory lesions of non-nodular acne vulgaris is not known.
成人の通常用量(添付文書の要約)
Acne vulgaris (inflammatory lesions of non-nodular moderate to severe), weight 33 to 54 kg: 60 mg orally once daily with or without food; reassess if no improvement after 12 weeks
妊娠と授乳
- 妊娠
- Unsafe May cause fetal harm, permanent tooth discoloration and reversible inhibition of bone growth; discontinue as soon as pregnancy is recognized.
- 授乳
- Unsafe Tetracyclines are excreted in human milk; breastfeeding is not recommended during therapy.
報告されている副作用
- Nausea
- Vulvovaginal mycotic infection
- Vulvovaginal candidiasis
禁忌
- Hypersensitivity to any of the tetracyclines.
注意が必要な方
- Use during tooth development (second and third trimesters, infancy, childhood up to age 8 years) may cause permanent tooth discoloration; can cause fetal harm.
- Clostridium difficile associated diarrhea can occur; discontinue if suspected or confirmed and not directed against C. difficile.
- CNS effects (light-headedness, dizziness, vertigo): caution about driving or hazardous machinery.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (104)
- Acitretin + Sarecycline Contraindicated
- Isotretinoin + Sarecycline Major
- Sarecycline + Tretinoin Major
- Aluminum hydroxide + Sarecycline Moderate
- Calcium + Sarecycline Moderate
- Calcium carbonate + Sarecycline Moderate
- Carbonyl iron + Sarecycline Moderate
- Cholestyramine + Sarecycline Moderate
- Chromium + Sarecycline Moderate
- Copper + Sarecycline Moderate
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Sarecyclineの完全なモノグラフ(用量、妊娠・授乳、副作用、警告、すべての相互作用)を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Sarecycline used for?
Sarecycline is a medicine in the class anti bacterial. It is used for Acne.
What side effects have been reported with Sarecycline?
Nausea, Vulvovaginal mycotic infection, Vulvovaginal candidiasis.
Can Sarecycline be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. May cause fetal harm, permanent tooth discoloration and reversible inhibition of bone growth; discontinue as soon as pregnancy is recognized. Breastfeeding: Unsafe. Tetracyclines are excreted in human milk; breastfeeding is not recommended during therapy.
What does Sarecycline interact with?
MediHelp lists 104 known interactions for Sarecycline. Contraindicated: 1 · Major: 2 · Moderate: 15 · Minor: 86. The most serious include Acitretin, Isotretinoin, Tretinoin.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。