相互作用
Levetiracetam + Opium tincture
重症度: 重大
Levetiracetam and Opium tincture: major interaction.
最終更新日
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概要
Opium tincture contains morphine and other opioids, which cause sedation and respiratory depression. Levetiracetam adds to drowsiness, increasing the risk of excessive sedation and breathing problems.
この相互作用をわかりやすく説明すると
Levetiracetam and Opium tincture can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Additive central nervous system and respiratory depression (pharmacodynamic).
対処法
Use the lowest effective opioid dose and monitor sedation and respiratory rate. Avoid adding further CNS depressants where possible.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、LevetiracetamとOpium tinctureの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Levetiracetamのその他の相互作用
よくある質問
Can I take Levetiracetam with Opium tincture?
MediHelp rates the interaction as major. Levetiracetam and Opium tincture can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Opium tincture contains morphine and other opioids, which cause sedation and respiratory depression. Levetiracetam adds to drowsiness, increasing the risk of excessive sedation and breathing problems.
How serious is the interaction between Levetiracetam and Opium tincture?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective opioid dose and monitor sedation and respiratory rate. Avoid adding further CNS depressants where possible.
What other medicines interact with Levetiracetam?
MediHelp also lists interactions of Levetiracetam with, for example, Oliceridine, Sodium oxybate, Sufentanil. The full list is on the Levetiracetam page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
