相互作用
Levetiracetam + Sufentanil
重症度: 重大
Levetiracetam and Sufentanil: major interaction.
最終更新日
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概要
Sufentanil is a very potent opioid that causes sedation and respiratory depression. Levetiracetam adds to drowsiness, increasing the risk of profound CNS depression.
この相互作用をわかりやすく説明すると
Levetiracetam and Sufentanil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Levetiracetam belongs to Central Nervous System; Sufentanil belongs to Musculoskeletal.
なぜ起こるのか
Additive central nervous system and respiratory depression (pharmacodynamic).
対処法
Use the lowest effective sufentanil dose and monitor sedation and respiratory function continuously in monitored settings.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、LevetiracetamとSufentanilの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Levetiracetamのその他の相互作用
Sufentanilのその他の相互作用
よくある質問
Can I take Levetiracetam with Sufentanil?
MediHelp rates the interaction as major. Levetiracetam and Sufentanil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Sufentanil is a very potent opioid that causes sedation and respiratory depression. Levetiracetam adds to drowsiness, increasing the risk of profound CNS depression.
How serious is the interaction between Levetiracetam and Sufentanil?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective sufentanil dose and monitor sedation and respiratory function continuously in monitored settings.
What other medicines interact with Levetiracetam?
MediHelp also lists interactions of Levetiracetam with, for example, Oliceridine, Opium tincture, Sodium oxybate. The full list is on the Levetiracetam page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
