相互作用
Magnesium + Roxadustat
重症度: 中等度
Magnesium and Roxadustat: moderate interaction.
最終更新日
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概要
Magnesium-containing products can bind roxadustat in the gut and reduce how much is absorbed. Lower exposure may blunt the haemoglobin response to treatment.
この相互作用をわかりやすく説明すると
Magnesium and Roxadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Magnesium belongs to Gastrointestinal Tract; Roxadustat belongs to Miscellaneous.
なぜ起こるのか
Chelation of roxadustat by multivalent cations in the gastrointestinal tract reduces its absorption.
対処法
Give roxadustat at least 1 hour after magnesium-containing products. Monitor haemoglobin and adjust roxadustat dose if the response is inadequate.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、MagnesiumとRoxadustatの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Roxadustatのその他の相互作用
Magnesiumのその他の相互作用
よくある質問
Can I take Magnesium with Roxadustat?
MediHelp rates the interaction as moderate. Magnesium and Roxadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium-containing products can bind roxadustat in the gut and reduce how much is absorbed. Lower exposure may blunt the haemoglobin response to treatment.
How serious is the interaction between Magnesium and Roxadustat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give roxadustat at least 1 hour after magnesium-containing products. Monitor haemoglobin and adjust roxadustat dose if the response is inadequate.
What other medicines interact with Roxadustat?
MediHelp also lists interactions of Roxadustat with, for example, Gemfibrozil, Probenecid, Atorvastatin. The full list is on the Roxadustat page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
