相互作用
Measles mumps and rubella vaccine + Oxaliplatin
重症度: 併用禁忌
Measles mumps and rubella vaccine and Oxaliplatin: contraindicated interaction.
最終更新日
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概要
Oxaliplatin-based chemotherapy causes myelosuppression and immune suppression, so the response to the live vaccine may be reduced. Replication of the vaccine viruses may be uncontrolled, which can cause serious vaccine-strain disease.
この相互作用をわかりやすく説明すると
Measles mumps and rubella vaccine and Oxaliplatin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Measles mumps and rubella vaccine belongs to Miscellaneous; Oxaliplatin belongs to Oncology.
なぜ起こるのか
Cytotoxic chemotherapy suppresses immune function, which blunts vaccine response and permits replication of live attenuated virus.
対処法
Do not give MMR during chemotherapy; give it at least 2 to 4 weeks before starting if feasible. After completion, delay vaccination for about 3 months and until immune recovery.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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アカウントを作成してPro+トライアルを始めると、Measles mumps and rubella vaccineとOxaliplatinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Measles mumps and rubella vaccineのその他の相互作用
- Adalimumab + Measles mumps and rubella vaccine 併用禁忌
- Anakinra + Measles mumps and rubella vaccine 併用禁忌
- Antithymocyte globulin equine + Measles mumps and rubella vaccine 併用禁忌
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine 併用禁忌
- Azathioprine + Measles mumps and rubella vaccine 併用禁忌
- Basiliximab + Measles mumps and rubella vaccine 併用禁忌
Oxaliplatinのその他の相互作用
- Adenovirus types 4 and 7 live + Oxaliplatin 併用禁忌
- Bcg vaccine live + Oxaliplatin 併用禁忌
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin 併用禁忌
- Measles mumps and rubella vaccine live + Oxaliplatin 併用禁忌
- Measles mumps rubella and varicella vaccine live + Oxaliplatin 併用禁忌
- Measles vaccine + Oxaliplatin 併用禁忌
よくある質問
Can I take Measles mumps and rubella vaccine with Oxaliplatin?
MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine and Oxaliplatin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oxaliplatin-based chemotherapy causes myelosuppression and immune suppression, so the response to the live vaccine may be reduced. Replication of the vaccine viruses may be uncontrolled, which can cause serious vaccine-strain disease.
How serious is the interaction between Measles mumps and rubella vaccine and Oxaliplatin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give MMR during chemotherapy; give it at least 2 to 4 weeks before starting if feasible. After completion, delay vaccination for about 3 months and until immune recovery.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。