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相互作用

Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil

重症度: 併用禁忌

Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil: contraindicated interaction.

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概要

This live attenuated combination vaccine can cause disseminated measles or varicella vaccine-strain disease in patients taking mycophenolate. Vaccine response may also be poor.

この相互作用をわかりやすく説明すると

Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

エビデンスレベル: High

なぜ起こるのか

Mycophenolate-induced lymphocyte suppression permits replication of live attenuated viruses.

対処法

Avoid during treatment and vaccinate at least 4 weeks before starting if feasible. Immunise household contacts and use post-exposure prophylaxis if exposed.

薬剤師に尋ねること

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+会員向け

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アカウントを作成してPro+トライアルを始めると、Measles mumps rubella and varicella vaccine liveとMycophenolate mofetilの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Measles mumps rubella and varicella vaccine live with Mycophenolate mofetil?

MediHelp rates the interaction as contraindicated. Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated combination vaccine can cause disseminated measles or varicella vaccine-strain disease in patients taking mycophenolate. Vaccine response may also be poor.

How serious is the interaction between Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during treatment and vaccinate at least 4 weeks before starting if feasible. Immunise household contacts and use post-exposure prophylaxis if exposed.

What other medicines interact with Mycophenolate mofetil?

MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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