相互作用
Measles vaccine + Mycophenolate mofetil
重症度: 併用禁忌
Measles vaccine and Mycophenolate mofetil: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Measles vaccine is live attenuated and can cause disseminated vaccine-strain infection in patients with significant immunosuppression. Mycophenolate may also reduce the immune response.
この相互作用をわかりやすく説明すると
Measles vaccine and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Impaired T and B cell function allows uncontrolled replication of live attenuated virus.
対処法
Avoid the vaccine during mycophenolate therapy. Give it at least 4 weeks before starting treatment if possible, and use immunoglobulin prophylaxis after exposure.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Measles vaccineとMycophenolate mofetilの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を7日間無料でお試し。カード登録不要。
Mycophenolate mofetilのその他の相互作用
- Adenovirus types 4 and 7 live + Mycophenolate mofetil 併用禁忌
- Bcg vaccine live + Mycophenolate mofetil 併用禁忌
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil 併用禁忌
- Measles mumps and rubella vaccine live + Mycophenolate mofetil 併用禁忌
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil 併用禁忌
- Mycophenolate mofetil + Rotavirus oral vaccine live 併用禁忌
よくある質問
Can I take Measles vaccine with Mycophenolate mofetil?
MediHelp rates the interaction as contraindicated. Measles vaccine and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated and can cause disseminated vaccine-strain infection in patients with significant immunosuppression. Mycophenolate may also reduce the immune response.
How serious is the interaction between Measles vaccine and Mycophenolate mofetil?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the vaccine during mycophenolate therapy. Give it at least 4 weeks before starting treatment if possible, and use immunoglobulin prophylaxis after exposure.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。