相互作用
Senna + Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol
重症度: 中等度
Senna and Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol: moderate interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Combining senna with a polyethylene glycol–based bowel preparation may increase the risk of colonic mucosal ulceration or ischemic colitis. It may also confound endoscopic assessment.
この相互作用をわかりやすく説明すると
Senna and Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Additive stimulant and osmotic effects on colonic motility and mucosa; mechanism not fully established.
対処法
Avoid additional stimulant laxatives during bowel preparation unless the procedural protocol specifies them. Counsel patients to report severe abdominal pain or rectal bleeding.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、SennaとSodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Sennaのその他の相互作用
よくある質問
Can I take Senna with Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol?
MediHelp rates the interaction as moderate. Senna and Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Combining senna with a polyethylene glycol–based bowel preparation may increase the risk of colonic mucosal ulceration or ischemic colitis. It may also confound endoscopic assessment.
How serious is the interaction between Senna and Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid additional stimulant laxatives during bowel preparation unless the procedural protocol specifies them. Counsel patients to report severe abdominal pain or rectal bleeding.
What other medicines interact with Senna?
MediHelp also lists interactions of Senna with, for example, Lily of the valley, Dichlorphenamide, Digoxin. The full list is on the Senna page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
