相互作用
Digoxin + Senna
重症度: 中等度
Digoxin and Senna: moderate interaction.
最終更新日
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概要
Prolonged or excessive senna use can cause diarrhea and potassium loss. Hypokalemia makes the heart more sensitive to digoxin and raises the risk of arrhythmias and digoxin toxicity.
この相互作用をわかりやすく説明すると
Digoxin and Senna can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Digoxin belongs to Cardiovascular; Senna belongs to Gastrointestinal Tract.
なぜ起こるのか
Laxative-induced gastrointestinal potassium loss produces hypokalemia, which enhances digoxin's cardiac toxicity.
対処法
Avoid prolonged senna use, and monitor serum potassium and magnesium in patients using it regularly. Correct electrolyte deficits and watch for signs of digoxin toxicity.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DigoxinとSennaの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Digoxinのその他の相互作用
Sennaのその他の相互作用
よくある質問
Can I take Digoxin with Senna?
MediHelp rates the interaction as moderate. Digoxin and Senna can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Prolonged or excessive senna use can cause diarrhea and potassium loss. Hypokalemia makes the heart more sensitive to digoxin and raises the risk of arrhythmias and digoxin toxicity.
How serious is the interaction between Digoxin and Senna?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid prolonged senna use, and monitor serum potassium and magnesium in patients using it regularly. Correct electrolyte deficits and watch for signs of digoxin toxicity.
What other medicines interact with Digoxin?
MediHelp also lists interactions of Digoxin with, for example, Lily of the valley, Squill, Adagrasib. The full list is on the Digoxin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
