Referência de medicamentos
Glatiramer
Glatiramer is a medicine in the class central nervous system. It is used for multiple sclerosis.
- Classe do medicamento: Central Nervous System
- Indicado para: multiple sclerosis
Última atualização Fontes: US FDA label
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Pontos-chave
- Classe do medicamento
- Central Nervous System
- Formas farmacêuticas comuns
- injeção
- Concentrações comuns
- 20 mg/ml, 40 mg/ml
- Interações conhecidas
- 18 (Leve: 18)
- Nomes comerciais
- 4
- Países e mercados
- 2
Para que é usado
Como funciona
Mechanism in MS is not fully understood; thought to act by modifying immune processes believed responsible for MS pathogenesis. Animal and in vitro studies suggest induction and activation of glatiramer acetate-specific suppressor T-cells in the periphery.
Dose habitual em adultos (resumo da bula)
Relapsing forms of multiple sclerosis: Glatopa 20 mg per mL, subcutaneous, once per day
Gravidez e amamentação
- Gravidez
- Unknown Pharmacovigilance and observational data have not identified a drug-associated risk of major birth defects, miscarriage, or adverse outcomes; no adverse effects in rats or rabbits.
- Amamentação
- Unknown No data on presence in human milk; low systemic exposure means clinically relevant infant exposure is not expected. Weigh benefits of breastfeeding against maternal need.
Efeitos adversos relatados
- Injection site erythema
- Injection site pain
- Injection site pruritus
- Injection site mass
- Vasodilatation
- Rash
Advertências de caixa preta
- Life-threatening and fatal anaphylaxis has been reported, and can occur at any time after starting therapy, from after the first dose to years later. Make patients aware of symptoms, which may overlap with immediate post-injection reaction, and instruct them to seek immediate medical care. Contraindicated in patients with prior hypersensitivity, including anaphylaxis. If anaphylaxis occurs, discontinue immediately and permanently unless a clear alternative etiology is identified.
Contraindicações
- Known hypersensitivity to glatiramer acetate or mannitol; reactions have included anaphylaxis.
Quem deve ter cuidado
- Immediate post-injection reaction (flushing, chest pain, palpitations, tachycardia, anxiety, dyspnea, throat constriction, urticaria) may occur within seconds to minutes after injection; usually transient.
- Transient chest pain may occur, often unrelated to injection.
- Lipoatrophy and rarely skin necrosis may occur at injection sites; lipoatrophy is thought to be permanent. Use proper technique and rotate sites.
Informe ao farmacêutico ou ao médico sobre gravidez ou amamentação, doença renal ou hepática, alergias e todos os outros medicamentos ou suplementos que você usa.
Principais interações (18)
- Anakinra + Glatiramer Minor
- Anti-thymocyte + Glatiramer Minor
- Basiliximab + Glatiramer Minor
- Denosumab + Glatiramer Minor
- Echinacea + Glatiramer Minor
- Etanercept + Glatiramer Minor
- Glatiramer + Golimumab Minor
- Glatiramer + Hepatitis A vaccine inactivated Minor
- Glatiramer + Human papillomavirus vaccine Minor
- Glatiramer + Leflunomide Minor
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para abrir a monografia completa de Glatiramer: doses, gravidez e amamentação, efeitos adversos, advertências e todas as interações.
- How to give it
- Pharmacokinetics
- Patient counselling points
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Outros medicamentos desta classe
Perguntas frequentes
What is Glatiramer used for?
Glatiramer is a medicine in the class central nervous system. It is used for Multiple sclerosis.
What side effects have been reported with Glatiramer?
Injection site erythema, Injection site pain, Injection site pruritus, Injection site mass, Vasodilatation, Rash. Serious warning: Life-threatening and fatal anaphylaxis has been reported, and can occur at any time after starting therapy, from after the first dose to years later.
Can Glatiramer be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Pharmacovigilance and observational data have not identified a drug-associated risk of major birth defects, miscarriage, or adverse outcomes; no adverse effects in rats or rabbits. Breastfeeding: Unknown. No data on presence in human milk; low systemic exposure means clinically relevant infant exposure is not expected. Weigh benefits of breastfeeding against maternal need.
What does Glatiramer interact with?
MediHelp lists 18 known interactions for Glatiramer. Minor: 18. The most serious include Anakinra, Anti-thymocyte, Basiliximab.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
