Interações medicamentosas
Abrocitinib + Ticlopidine
Gravidade: Grave
Abrocitinib and Ticlopidine: major interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Abrocitinib lowers platelet count and function early in treatment, and ticlopidine also impairs platelet function and can cause thrombocytopenia. Together they increase bleeding risk. Labeling advises against antiplatelets except low-dose aspirin in the first three months.
O que esta interação significa em palavras simples
Abrocitinib and Ticlopidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Abrocitinib belongs to Miscellaneous; Ticlopidine belongs to Cardiovascular.
Por que acontece
Additive impairment of platelet function and count.
O que fazer
Avoid the combination in the first three months of abrocitinib. Monitor platelet counts and for bleeding if it cannot be avoided.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Abrocitinib e Ticlopidine, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 7 dias na web. Sem cartão.
Outras interações de Ticlopidine
Outras interações de Abrocitinib
- Abrocitinib + Upadacitinib Contraindicada
- Abciximab + Abrocitinib Grave
- Abrocitinib + Anagrelide Grave
- Abrocitinib + Cilostazol Grave
- Abrocitinib + Clopidogrel Grave
- Abrocitinib + Eptifibatide Grave
Perguntas frequentes
Can I take Abrocitinib with Ticlopidine?
MediHelp rates the interaction as major. Abrocitinib and Ticlopidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Abrocitinib lowers platelet count and function early in treatment, and ticlopidine also impairs platelet function and can cause thrombocytopenia. Together they increase bleeding risk. Labeling advises against antiplatelets except low-dose aspirin in the first three months.
How serious is the interaction between Abrocitinib and Ticlopidine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in the first three months of abrocitinib. Monitor platelet counts and for bleeding if it cannot be avoided.
What other medicines interact with Ticlopidine?
MediHelp also lists interactions of Ticlopidine with, for example, Mavacamten, Acetylsalicylic acid, Apixaban. The full list is on the Ticlopidine page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
