Interações medicamentosas
Acetylsalicylic acid + Bismuth subsalicylate
Gravidade: Moderada
Acetylsalicylic acid and Bismuth subsalicylate: moderate interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Bismuth subsalicylate is hydrolysed to release salicylate, so taking it with aspirin adds to the total salicylate load. This can raise the risk of salicylate toxicity such as tinnitus and gastrointestinal bleeding, especially with repeated or high dosing.
O que esta interação significa em palavras simples
Acetylsalicylic acid and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Acetylsalicylic acid belongs to Musculoskeletal; Bismuth subsalicylate belongs to Gastrointestinal Tract.
Por que acontece
Additive salicylate exposure and additive antiplatelet and gastrointestinal mucosal effects.
O que fazer
Avoid routine concurrent use of bismuth subsalicylate with analgesic-dose aspirin and limit duration. Monitor for tinnitus, GI bleeding and bruising, particularly in older adults and those on anticoagulants.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Acetylsalicylic acid e Bismuth subsalicylate, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Outras interações de Acetylsalicylic acid
- Acetylsalicylic acid + Ketorolac Contraindicada
- Acetylsalicylic acid + Ketorolac intranasal Contraindicada
- Abciximab + Acetylsalicylic acid Grave
- Acemetacin + Acetylsalicylic acid Grave
- Acetazolamide + Acetylsalicylic acid Grave
- Acetylsalicylic acid + Alteplase Grave
Outras interações de Bismuth subsalicylate
Perguntas frequentes
Can I take Acetylsalicylic acid with Bismuth subsalicylate?
MediHelp rates the interaction as moderate. Acetylsalicylic acid and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bismuth subsalicylate is hydrolysed to release salicylate, so taking it with aspirin adds to the total salicylate load. This can raise the risk of salicylate toxicity such as tinnitus and gastrointestinal bleeding, especially with repeated or high dosing.
How serious is the interaction between Acetylsalicylic acid and Bismuth subsalicylate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine concurrent use of bismuth subsalicylate with analgesic-dose aspirin and limit duration. Monitor for tinnitus, GI bleeding and bruising, particularly in older adults and those on anticoagulants.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
