Interações medicamentosas
Acetylsalicylic acid + Eptifibatide
Gravidade: Grave
Acetylsalicylic acid and Eptifibatide: major interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Eptifibatide is a potent glycoprotein IIb/IIIa inhibitor, and aspirin adds to bleeding risk. The combination is standard in acute coronary syndromes and PCI but requires close bleeding surveillance.
O que esta interação significa em palavras simples
Acetylsalicylic acid and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Acetylsalicylic acid belongs to Musculoskeletal; Eptifibatide belongs to Cardiovascular.
Por que acontece
Additive platelet inhibition from blockade of the GP IIb/IIIa receptor and irreversible COX-1 inhibition.
O que fazer
Use under supervised protocols with renally adjusted eptifibatide dosing and low-dose aspirin. Monitor for bleeding, hemoglobin and platelet counts.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Acetylsalicylic acid
- Acetylsalicylic acid + Ketorolac Contraindicada
- Acetylsalicylic acid + Ketorolac intranasal Contraindicada
- Abciximab + Acetylsalicylic acid Grave
- Acemetacin + Acetylsalicylic acid Grave
- Acetazolamide + Acetylsalicylic acid Grave
- Acetylsalicylic acid + Alteplase Grave
Outras interações de Eptifibatide
Perguntas frequentes
Can I take Acetylsalicylic acid with Eptifibatide?
MediHelp rates the interaction as major. Acetylsalicylic acid and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Eptifibatide is a potent glycoprotein IIb/IIIa inhibitor, and aspirin adds to bleeding risk. The combination is standard in acute coronary syndromes and PCI but requires close bleeding surveillance.
How serious is the interaction between Acetylsalicylic acid and Eptifibatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use under supervised protocols with renally adjusted eptifibatide dosing and low-dose aspirin. Monitor for bleeding, hemoglobin and platelet counts.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
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