Interações medicamentosas
Aclidinium + Glycopyrronium
Gravidade: Moderada
Aclidinium and Glycopyrronium: moderate interaction.
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Resumo
Both drugs are antimuscarinics, so combining them gives additive anticholinergic effects such as dry mouth, urinary retention, constipation and raised intraocular pressure. Duplicate therapy provides little added benefit.
O que esta interação significa em palavras simples
Aclidinium and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Additive muscarinic receptor antagonism.
O que fazer
Avoid concurrent use of two antimuscarinic bronchodilators or anticholinergics; if combined, monitor for urinary retention, glaucoma symptoms and constipation.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Glycopyrronium
- Clozapine + Glycopyrronium Grave
- Abobotulinumtoxina + Glycopyrronium Moderada
- Amantadine + Glycopyrronium Moderada
- Amitriptyline + Glycopyrronium Moderada
- Amoxapine + Glycopyrronium Moderada
- Atropine iv / + Glycopyrronium Moderada
Perguntas frequentes
Can I take Aclidinium with Glycopyrronium?
MediHelp rates the interaction as moderate. Aclidinium and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are antimuscarinics, so combining them gives additive anticholinergic effects such as dry mouth, urinary retention, constipation and raised intraocular pressure. Duplicate therapy provides little added benefit.
How serious is the interaction between Aclidinium and Glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use of two antimuscarinic bronchodilators or anticholinergics; if combined, monitor for urinary retention, glaucoma symptoms and constipation.
What other medicines interact with Glycopyrronium?
MediHelp also lists interactions of Glycopyrronium with, for example, Clozapine, Abobotulinumtoxina, Amantadine. The full list is on the Glycopyrronium page.
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