Interações medicamentosas
Atropine iv / + Glycopyrronium
Gravidade: Moderada
Atropine iv / and Glycopyrronium: moderate interaction.
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Resumo
Both are antimuscarinics, so their combination adds to anticholinergic effects including tachycardia, dry mouth, urinary retention and reduced gut motility. This is often intentional perioperatively but can lead to excessive effects.
O que esta interação significa em palavras simples
Atropine iv / and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Additive muscarinic receptor blockade.
O que fazer
Avoid unnecessary duplication; monitor heart rate, and watch for urinary retention, ileus and delirium, particularly in elderly patients.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Glycopyrronium
- Clozapine + Glycopyrronium Grave
- Abobotulinumtoxina + Glycopyrronium Moderada
- Aclidinium + Glycopyrronium Moderada
- Amantadine + Glycopyrronium Moderada
- Amitriptyline + Glycopyrronium Moderada
- Amoxapine + Glycopyrronium Moderada
Perguntas frequentes
Can I take Atropine iv / with Glycopyrronium?
MediHelp rates the interaction as moderate. Atropine iv / and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are antimuscarinics, so their combination adds to anticholinergic effects including tachycardia, dry mouth, urinary retention and reduced gut motility. This is often intentional perioperatively but can lead to excessive effects.
How serious is the interaction between Atropine iv / and Glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unnecessary duplication; monitor heart rate, and watch for urinary retention, ileus and delirium, particularly in elderly patients.
What other medicines interact with Glycopyrronium?
MediHelp also lists interactions of Glycopyrronium with, for example, Clozapine, Abobotulinumtoxina, Aclidinium. The full list is on the Glycopyrronium page.
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