Interações medicamentosas
Aclidinium + Oxybutynin
Gravidade: Moderada
Aclidinium and Oxybutynin: moderate interaction.
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Resumo
Both are antimuscarinic agents, so combined use may add anticholinergic effects such as dry mouth, constipation, urinary retention and blurred vision. Systemic exposure to inhaled aclidinium is low, limiting the effect.
O que esta interação significa em palavras simples
Aclidinium and Oxybutynin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Additive muscarinic receptor antagonism.
O que fazer
Monitor for urinary retention, constipation and angle-closure glaucoma symptoms, particularly in older patients.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Oxybutynin
Perguntas frequentes
Can I take Aclidinium with Oxybutynin?
MediHelp rates the interaction as moderate. Aclidinium and Oxybutynin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are antimuscarinic agents, so combined use may add anticholinergic effects such as dry mouth, constipation, urinary retention and blurred vision. Systemic exposure to inhaled aclidinium is low, limiting the effect.
How serious is the interaction between Aclidinium and Oxybutynin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for urinary retention, constipation and angle-closure glaucoma symptoms, particularly in older patients.
What other medicines interact with Oxybutynin?
MediHelp also lists interactions of Oxybutynin with, for example, Bethanechol, Clozapine, Potassium chloride. The full list is on the Oxybutynin page.
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